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  June 1998 -- and Abnormal 

People With Fetal Alcohol Syndrome Suffer All Their Lives

Overview | Article Summary | For Instructors | For Students
 

Famy, C., Streissguth, A.P., and Unis, A.s. (1998) Mental illness in adults with fetal alcohol syndrome or fetal alcohol effects American Journal of Psychiatry, 155, 552-554. 

Overview:

Fetal Alcohol Syndrome

Prenatal exposure to alcohol can be associated with a wide range of abnormalities. Children with fetal alcohol syndrome (FAS) may have physical abnormalities, such as microcephaly (abnormally small head), eye and ear abnormalities, heart defects, and poor motor coordination. They also have psychological impairments, such as mild to moderate mental retardation, attention deficit disorder with hyperactivity, and conduct disorders. Some children do not manifest physical abnormalities but still have intellectual difficulties, attention deficit disorder with hyperactivity, motor coordination problems, and conduct disorders. These children are classified as having fetal alcohol effects (FAE). 

FAS/FAE is one of the most preventable causes of mental retardation. A large amount of research has established that there is no safe amount of alcohol consumption during pregnancy. Pregnant women are constantly warned - by physicians, through advertising, and on warning labels - not to drink during pregnancy. Even so, FAS/FAE is one of the leading causes of mental retardation in North America. 

Educational programs have been developed to deal with the special problems that children with FAS/FAE experience while growing up. What about adults with FAS/FAE? Very little research has been done to identify long term effects of FAS/FAE. Famy, Streissguth, and Unis (1998) examined psychological problems in adults with FAS/FAE as part of a longitudinal study of the effects of prenatal exposure to alcohol. 

Overview | Article Summary | For Instructors | For Students

Article Summary

Individuals with behavior control difficulties as children have a strong tendency to develop psychiatric problems as adults. Do children with FAS/FAE, developmental disorders characterized by behavioral problems, such as attention deficit with hyperactivity, impulsivity, and conduct disorders, have a high rate of psychiatric problems? Famy, Streissguth, and Unis (1998) addressed this question. 

They conducted structured interviews of individuals involved in a longitudinal study of FAS/FAE to determine the degree and nature of psychiatric problems experienced by adults with FAS/FAE. The structured interviews were used to diagnose Axis I (Clinical Syndromes) and Axis II (Personality Disorders) as laid out in the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition-revised and 4th edition (DSM-III and DSM-IV). Axis I diagnoses are more severe and debilitating disorders, such as substance-related disorders, anxiety disorders, mood disorders, and psychotic disorders. Axis II diagnoses are less severe personality disturbances, such as avoidant personality disorder, antisocial personality disorder, and dependent personality disorder. 

Recent epidemiological studies have determined that approximately one-third of the population has experienced a psychological disorder. Famy et al, diagnosed 92% of their sample with an Axis I disorder and 48% with an Axis II disorder. Many people received multiple diagnoses. 

The most common Axis I diagnosis was a substance-related disorder (60%). Major depression and psychotic disorders were next most common (44% and 40%, respectively). Anxiety disorders and eating disorders were also common (20% each). With the exception of anxiety disorders, these diagnoses are two to four times greater than found in the general population. These disorders were approximately equally distributed across gender and across FAS/FAE diagnosis. 

Though potentially less personally debilitating, Axis II diagnoses were also quite high. The most common diagnoses were avoidant personality disorder (29%), antisocial personality disorder (19%), and dependent personality disorder (14%). 

According to their self-reports, over 70% of the sample had received some form of psychiatric treatment, and one-third of these people had been hospitalized. 

Famy et al.'s results indicate that adults with FAS/FAE have a very high rate of mental illness. Although the sample size was somewhat small, there is no indication that this group was particularly extreme. This study extends the debilitating effect of prenatal alcohol exposure on development into adulthood. The fact that FAS/FAE can be prevented makes these findings all the more upsetting. 

Overview | Article Summary | For Instructors | For Students

For Instructors

Links to the Lecture

There are a number of excellent videos on prenatal drug and alcohol exposure and FAS/FAE: 
    Sacred Trust; Protect Your Baby Against Fetal Alcohol Syndrome (1992, USDA, 14 min.). This video addresses Fetal Alcohol Syndrome (FAS) and Fetal Alcohol Effects (FAE) among Native American women. 

    The Mind: Fetal Alcohol Syndrome (1988, PBS, 5 min.). 

Overview | Article Summary | For Instructors | For Students

For Students

About the Authors

Chris Famy is a student in the University of Washington School of Medicine. Ann Streissguth and Alan Unis are professors in Department of Psychiatry and Behavioral Sciences at the University of Washington School of Medicine. Dr. Streissguth directs the Fetal Alcohol and Drug Unit which conducts longitudinal studies of children with FAS/FAE and families with alcohol and drug abuse. 

About the Journal

The American Journal of Psychiatry publishes a wide range of articles reporting experimental research, case studies, and reviews dealing with psychiatric medicine and clinical research. 

Links to Life

Lean more about FAS/FAE

  • The League For The Prevention of Alcohol Related Fetal Brain Injury provides a wealth of on-line information and links related to FAS. 
  • This policy statement on FAS/FAE from the American Association of Pediatrics includes information about symptoms, treatment, and prevention. 
  • Read these cogent arguments against alcohol use during pregnancy written by medical school professors. 
 

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